Abiprot Select™- The target selection algorithm

Abiprot is used together with the target selection algorithm Abiprot Select™, forming a powerful proteomics-bioinformatics platform. Abiprot Select is essentially an algorithm or set of rules for target selection and epitope validation that eliminates risk and significantly reduces cost and development time. One of the criteria is that the target must either be clinically validated or have compelling evidence of efficacy from human genetics studies.Thus, targets we select are typically those that have been tried with small molecules and met efficacy endpoints in a phase 2b or later study but failed over all due to toxicity.

 

 

We generate relatively small panels of high-quality antibody leads, and typically, we can advance into lead optimization in a very short period of time