– The target selection algorithm
An algorithm for target selection
AbiprotTM is used with the target selection algorithm Abiprot Select™ to form a powerful proteomics-bioinformatics platform. Abiprot Select™ is essentially an algorithm or set of rules for target selection and epitope validation that eliminates risk and significantly reduces costs and development time.
Removing toxicity from the equation
One of the criterion is that the target must either be clinically validated or have compelling evidence of efficacy from human genetics studies. The targets we select have therefore typically been tested with small molecules and met efficacy endpoints in a phase 2b study or later but failed overall due to toxicity.